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🔥Weight Loss & Fat Burning

Peptides targeting fat metabolism, appetite suppression, and body composition improvement through GLP-1 receptor activation, lipolysis, or metabolic enhancement.

Semaglutide

Relevance: 10/10GLP-1 Receptor Agonist

An FDA-approved GLP-1 receptor agonist used for type 2 diabetes and chronic weight management, producing significant weight loss of 15-17% body weight in clinical trials.

Tirzepatide

Relevance: 10/10Dual GIP/GLP-1 Receptor Agonist

A first-in-class dual GIP/GLP-1 receptor agonist that produces up to 22.5% body weight loss, approved for type 2 diabetes and obesity management.

Tesamorelin

Relevance: 10/10Growth Hormone Secretagogue (GHRH Analogue)

An FDA-approved synthetic analogue of growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification, indicated for HIV-associated lipodystrophy and studied for cognitive benefits and visceral fat reduction.

GHRP-6

Relevance: 10/10Growth Hormone Secretagogue (Ghrelin Mimetic)

A synthetic hexapeptide growth hormone secretagogue that stimulates GH release through the ghrelin receptor (GHS-R1a), notable for its potent GH-releasing effects and strong appetite stimulation.

HGH Fragment 176-191

Relevance: 10/10Fat Loss / Metabolic Peptide

A modified fragment of human growth hormone (amino acids 176-191) that specifically promotes fat metabolism and lipolysis without the growth-promoting or diabetogenic effects of full HGH.

5-Amino-1MQ

Relevance: 10/10Metabolic / Fat Loss Compound (NNMT Inhibitor)

A small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that promotes fat loss by increasing NAD+ levels and cellular energy metabolism, available as an oral compound.

Tesofensine

Relevance: 10/10Weight Loss / CNS Compound (Triple Reuptake Inhibitor)

A triple monoamine reuptake inhibitor (serotonin, norepinephrine, dopamine) originally developed for Parkinson's and Alzheimer's disease, repurposed as a potent weight-loss agent.

GHRP-2

Relevance: 8/10Growth Hormone Secretagogue

A synthetic hexapeptide growth hormone secretagogue considered to offer the best balance of potency and side effect profile among the GHRP family.

Hexarelin

Relevance: 8/10Growth Hormone Secretagogue

A synthetic hexapeptide growth hormone secretagogue that potently stimulates GH release through the ghrelin receptor, with additional cardioprotective properties.

CJC-1295 (no DAC) / Mod GRF 1-29

Relevance: 7/10Growth Hormone Secretagogue (GHRH Analog)

A modified growth hormone-releasing hormone fragment with a short half-life (~30 minutes) that stimulates pulsatile growth hormone release, closely mimicking the body's natural GH secretion pattern.

CJC-1295 (with DAC)

Relevance: 7/10Growth Hormone Secretagogue (GHRH Analog)

A long-acting growth hormone-releasing hormone (GHRH) analog with a Drug Affinity Complex that extends its half-life to 6-8 days, producing sustained elevated growth hormone and IGF-1 levels.

MOTS-c

Relevance: 7/10Mitochondria-Derived Peptide

A mitochondria-derived peptide that acts as an exercise mimetic, improving metabolic health, insulin sensitivity, and physical performance through AMPK activation.

Ipamorelin

Relevance: 6/10Growth Hormone Secretagogue (GHRP)

A highly selective growth hormone-releasing peptide (GHRP) that stimulates GH release with minimal impact on cortisol, prolactin, or appetite, making it the cleanest GHRP available.

SS-31 (Elamipretide)

Relevance: 6/10Mitochondria-Targeted Peptide

A mitochondria-targeted tetrapeptide that concentrates in the inner mitochondrial membrane, protecting cardiolipin and restoring bioenergetics in aging and disease.

MK-677 (Ibutamoren)

Relevance: 5/10Growth Hormone Secretagogue (Non-Peptide, Oral GHS)

An orally active, non-peptide growth hormone secretagogue that mimics ghrelin to raise GH and IGF-1 levels for up to 24 hours per dose, with notable effects on sleep, appetite, and body composition.

Sermorelin

Relevance: 5/10Growth Hormone Secretagogue (GHRH Analog)

The first 29 amino acids of natural GHRH, previously FDA-approved for pediatric GH deficiency. Now widely used off-label for anti-aging GH optimization as a safer alternative to direct HGH therapy.