👴Anti-Aging & Longevity
Peptides targeting aging mechanisms including telomere maintenance, senescent cell clearance, mitochondrial function, and cellular repair pathways.
Retatrutide
Relevance: 10/10Triple Incretin Receptor AgonistAn investigational triple-agonist peptide targeting GLP-1, GIP, and glucagon receptors, producing unprecedented weight loss of up to 24% in clinical trials.
AOD 9604
Relevance: 10/10Fat Loss / Metabolic PeptideA modified fragment of human growth hormone (amino acids 176-191) that stimulates lipolysis and inhibits lipogenesis without the diabetogenic or growth-promoting effects of full-length HGH.
Survodutide
Relevance: 10/10Dual Glucagon/GLP-1 Receptor AgonistAn investigational dual glucagon and GLP-1 receptor agonist being developed for obesity and MASH (metabolic dysfunction-associated steatohepatitis) with significant liver fat reduction.
Liraglutide
Relevance: 9/10GLP-1 Receptor AgonistAn FDA-approved GLP-1 receptor agonist used for type 2 diabetes and obesity management, with cardiovascular and neuroprotective benefits.
GHK-Cu
Relevance: 9/10Copper Peptide / Skin & Healing PeptideA naturally occurring copper-binding tripeptide that declines with age, known for potent wound healing, collagen stimulation, anti-aging skin effects, and hair growth promotion.
Sermorelin
Relevance: 9/10Growth Hormone Secretagogue (GHRH Analog)The first 29 amino acids of natural GHRH, previously FDA-approved for pediatric GH deficiency. Now widely used off-label for anti-aging GH optimization as a safer alternative to direct HGH therapy.
Tesamorelin
Relevance: 9/10Growth Hormone Secretagogue (GHRH Analogue)An FDA-approved synthetic analogue of growth hormone-releasing hormone (GHRH) with a trans-3-hexenoic acid modification, indicated for HIV-associated lipodystrophy and studied for cognitive benefits and visceral fat reduction.
CJC-1295 (with DAC)
Relevance: 8/10Growth Hormone Secretagogue (GHRH Analog)A long-acting growth hormone-releasing hormone (GHRH) analog with a Drug Affinity Complex that extends its half-life to 6-8 days, producing sustained elevated growth hormone and IGF-1 levels.
Thymalin
Relevance: 8/10Immune / Bioregulatory PeptideA thymic peptide bioregulator developed in Russia that restores immune function by promoting T-cell maturation and has shown anti-aging effects in clinical studies on elderly patients.
Ipamorelin
Relevance: 7/10Growth Hormone Secretagogue (GHRP)A highly selective growth hormone-releasing peptide (GHRP) that stimulates GH release with minimal impact on cortisol, prolactin, or appetite, making it the cleanest GHRP available.
MK-677 (Ibutamoren)
Relevance: 7/10Growth Hormone Secretagogue (Non-Peptide, Oral GHS)An orally active, non-peptide growth hormone secretagogue that mimics ghrelin to raise GH and IGF-1 levels for up to 24 hours per dose, with notable effects on sleep, appetite, and body composition.
CJC-1295 (no DAC) / Mod GRF 1-29
Relevance: 7/10Growth Hormone Secretagogue (GHRH Analog)A modified growth hormone-releasing hormone fragment with a short half-life (~30 minutes) that stimulates pulsatile growth hormone release, closely mimicking the body's natural GH secretion pattern.
Melanotan II
Relevance: 7/10Melanocortin Receptor AgonistA synthetic cyclic peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) that induces skin tanning, increases libido, and reduces appetite through melanocortin receptor activation.
Dulaglutide
Relevance: 7/10GLP-1 Receptor AgonistAn FDA-approved once-weekly GLP-1 receptor agonist for type 2 diabetes with proven cardiovascular benefits and convenient single-use pen delivery.
Exenatide
Relevance: 7/10GLP-1 Receptor AgonistThe first GLP-1 receptor agonist approved for type 2 diabetes, originally derived from Gila monster venom, available in twice-daily and once-weekly formulations.
Dihexa
Relevance: 7/10Cognitive Enhancement PeptideAn oligopeptide derived from angiotensin IV that is reported to be 10 million times more potent than BDNF at enhancing cognitive function through hepatocyte growth factor (HGF) signaling.
Cerebrolysin
Relevance: 7/10Neuroprotective Peptide MixtureA porcine brain-derived peptide preparation containing low-molecular-weight neuropeptides and free amino acids, used clinically in many countries for stroke recovery, traumatic brain injury, and dementia.
P21
Relevance: 7/10Cognitive Enhancement / Nootropic PeptideA small synthetic peptide derived from ciliary neurotrophic factor (CNTF) that promotes neurogenesis and enhances cognitive function by inhibiting leukemia inhibitory factor (LIF) signaling.
Thymulin
Relevance: 7/10Immune / Thymic Peptide HormoneA zinc-dependent nonapeptide hormone produced by thymic epithelial cells that plays an essential role in T-cell differentiation and immune regulation, declining significantly with age.
5-Amino-1MQ
Relevance: 6/10Metabolic / Fat Loss Compound (NNMT Inhibitor)A small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that promotes fat loss by increasing NAD+ levels and cellular energy metabolism, available as an oral compound.
Matrixyl
Relevance: 6/10Cosmeceutical / Signal PeptideA lipopeptide used in cosmetic skincare that stimulates collagen and extracellular matrix production, often marketed as a non-invasive alternative to retinol for anti-wrinkle treatment.
Argireline
Relevance: 5/10Cosmeceutical / Neuromuscular PeptideA synthetic hexapeptide that inhibits neurotransmitter release at the neuromuscular junction, reducing facial muscle contraction and wrinkle formation — often called 'Botox in a bottle'.
Melanotan I
Relevance: 4/10Melanocortin PeptideA synthetic analog of alpha-melanocyte stimulating hormone (α-MSH) that stimulates melanin production for photoprotection, FDA-approved (as Scenesse) for erythropoietic protoporphyria (EPP).
Pentosan Polysulfate
Relevance: 4/10Joint Health / Disease-Modifying CompoundA semi-synthetic polysaccharide (heparin-like compound) used clinically for interstitial cystitis and osteoarthritis, with disease-modifying effects on cartilage, joints, and the glycosaminoglycan layer.